Do you use enzymes? Have you found any that you've had success with? What kind of success?
Do you take the Big 3 or anything else?
Thanks,
Ellen

@bolso1 I have wondered if these bugs multiply in our mouths and then are sucked in to out lungs at night while breathing. Sorry a bit off the topic but have often wondered. Take care Heather

Yes @bolso1, me too -- I've seen some research in the past, and more recently, on enzymes and biofilms in the body and many other applications. But so far, no enzyme lung treatments yet for NTM biofilms.
(NB. Folks, some enzymes have been sold in shops or online for a while, but unfortunately, most are for the gut and digestion -- no use for the lungs. Sadly, they cannot help us with NTMs).
In recent years, there's been a little research on enzymes for biofilms in the lungs that's more promising -- e.g. for Pseudomonas Aeroginosa in people with Cystic Fibrosis etc. For example, getting an enzyme like pyruvate dehydrogenase (NOT pyruvate dehydrogenase kinase) with an antibiotic like Tobramycin -- so the biofilm from p.Aeroginosa is attacked as well as the bug. But there are some risks. And there's no inhalable drug yet -- or any research for an inhalable drug yet.
Unfortunately, nobody should 'hold their breath' waiting for a treatment of this kind. A lot of this research is very small-scale and unfunded, or given very little funding. It might not be taken up by drug companies for decades, if ever -- unless there's an ongoing, public push for it.
The so-called 'big 3' we're often given for NTMs are 3 antibiotics that have actually been around for 60 years! Good grief, 60 years!
Back in those days researchers didn't know much about biofilms, and many still don't These drugs have also been inherited from other illnesses -- e.g. Tuberculosis, or Leprosy.
Additionally, some of our doctors and pulmonologists either aren't 'awake' to the fact that drug companies really only test new drugs on free-floating planktonic bacteria, but not on the bacterial biofilms as well (because they'd need dangerously high doses to get through biofilms); or they're just pragmatic -- they're only going to treat NTMs with what's already available. Period.
But one thing Covid19 has taught us: it's really just a matter of 'will' how quickly research gets done -- and a matter of increased funding for medical research and medical applications.