I am not sure what your research was. Can you share? My daughter has had incredible success with PRP, a form of prolotherapy. The doctor works for a rehab organization that is part of Mass. General Hospital-a top hospital in the world- and has reams of years long research. The doc very carefully screens patients, using imaging and requiring PT first, so that those who have PRP are those who can most benefit. PRP works with soft tissue problems, not anything related to bones. It most definitely works for those it is intended for, and is not quackery.