I wanted to mention that Omeprazole was prescribed for me for several years by a physician. Endoscopy had shown eosinophilic, and Barrett's cells. There was reflux, and a hernia. This was bumped up to a higher dose, but really didn't help that much. A couple years later I happened to have a genetic test that was needed to determine how I metabolized certain drugs. The results came out that I was a very fast metabolizer. Omeprazole was one of the drugs that was affected by this genetic condition. I was told to switch to another PPI since I'd never get relief with the Omeprazole.