The prednisone really did not make a dent on my breathlessness but glad I tried it, as it is supposed to reduce inflammation. I did send in a sputum sample last week and just today got the news that I have a bacteria called "Achromobacter". This may very well be the culprit. Has anyone out there been diagnosed with this? The best drug to treat this is Bactrim from what I understand. If anyone has anything to offer in the way of experience or information on this bacteria, please let me know. Thanks, Pam