Hello @guderianj and welcome to Mayo Clinic Connect. I appreciate your post about hemiplegic migraine. We do have other members on Connect who have spoken about this such as @azza1 and @gtownsend. I hope they will join this discussion.

I looked on Mayo Clinic's website and see that there is a Clinical Trial for medication for these types of migraines. Here is a link to that Clinical Trial https://www.mayo.edu/research/clinical-trials/cls-20305353?_ga=2.127727566.273405985.1641077529-1603362872.1610991398, The Clinical Trial is closed now.

As you are comfortable doing so, please share a bit more about your history of migraines. Have you had auras and one-side weakness and/or paralysis? How long do your migraines generally last? What type of meds are you taking?

Here is a link to a video by a Mayo neurologist, discussing his history of migraines that you might find interesting.