@videlia As you will learn from reading the various threads here, everybody has a different experience with the antibiotics. If you haven't scanned through some of them, you might try - at the main MAC group page (https://connect.mayoclinic.org/group/mac-bronchiectasis/), you can scroll down and find some that interest you. I was on them for 18 months, and gradually my body learned to tolerate. I developed a system of taking them near bedtime because my days were too miserable if I did it in the morning. I also used ginger tea to ease my stomach, ate yogurt and took probiotics to protect my system. Other people develop other strategies for coping. If you experience loss of appetite and unwanted weight loss, you could try frequent small meals or snacks of protein-rich foods like nuts & cheese.
Did you receive any counseling from your doctor or pharmacist on what to expect, how to manage, etc? Were you given a name and phone number to contact with questions? In my case, the pulmonologist wasn't very helpful, but his nurse was wonderful, and always willing to answer questions and/or find information for me.