Scans while on Lupron are not very effective. It shrinks the cancer making it almost impossible to find even with the better scans. You need the scans while off Lupron and you need the C11Choline or PSMA scans which are much more precise. That’s why I switched my care to Mayo who were able to find my cancer that the other scans missed. I suggest going to a specialist who deals with salvage radical prostatectomies. Don’t panic,if the Lupron is working as it usually does on most people it buys you time.