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Triple Negative Breast Cancer: What treatments are you having?
Breast Cancer | Last Active: Sep 6 11:41am | Replies (244)Comment receiving replies
The clinical manifestation of triple-negative breast cancer is an aggressive course, with a higher risk of distant metastasis, a higher chance of visceral metastasis than bone metastasis, and a higher chance of brain metastasis. The risk of distant metastasis of triple-negative breast cancer reaches its peak at 3 years, and may decrease thereafter. The median tumor size of triple-negative breast cancer is 2 cm, and 50% have lymph node metastasis. The histological grade of this type of breast cancer is mostly grade 3, and the proportion of cell proliferation is relatively high.
Treatment
There are no specific treatment guidelines for triple-negative breast cancer. Therefore, its treatment is generally carried out according to the conventional standard treatment of breast cancer.
1. Chemotherapy
Compared with other types of breast cancer, chemotherapy is more effective for triple-negative breast cancer, but if it is just a conventional standard treatment, the prognosis is still very poor.
2. Adjuvant chemotherapy
FEC sequential docetaxel chemotherapy has a better response. Taxanes have a certain effect on triple-negative breast cancer. Platinum drugs may be more effective in triple-negative breast cancer. Cisplatin neoadjuvant chemotherapy is quite effective.
Replies to "The clinical manifestation of triple-negative breast cancer is an aggressive course, with a higher risk of..."
Hi, @medical01 Can you tell me where this information is from? I had surgery and chemotherapy (taxotere and cytoxan) ending the last of January 2022 after a triple-negative diagnosis a year ago. I am trying to be realistic going forward, which means finding out the full extent of what I *can* know about risks and statistics while still nurturing a life-affirming attitude so I can make the best use of my time every day. While I can't know my own future health, it does help my perspective to to be as aware as possible of the medical facts as they stand at the present time. That's the long way around the core of my question, which is this: I am just wondering where your information is from. As I have searched to find out prognosis statistics on triple-negative breast cancer, I have found Mayo's online information to be the most straightforward and least patronizing, which I appreciate as a patient. (I live in Washington state, so I am unbiased in terms of my care team having no affiliation with Mayo!) But you have some details in this write-up I have not seen before, although admittedly it has been a couple of months since I have done intensive searching--and besides, I am a layperson and thus I don't have quite the same access to medical details as a professional! Anyway, I appreciate what you have shared and would be interested in what I can find out further. For instance: One question I'd ask if you are "in the business" is what's the backstory on Zometa (zoledronic acid), which I am being given every six months for two years following the end of my chemo. My oncologist says it will reduce the chance of a metastasis by 1%. I'll take any reduction, but I am wondering if the Zometa's effect is primarily seen in reducing the likelihood of cancer in bone instead of in other areas.
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Thank you for the TNBC 101 class, I think it helps us all to have more information. Maybe in the future research can solve the problem of not having a druggable target in TNBC, and make this an easier path for patients and provide clearer treatment plans for clinicians. Without a clear path to move forward it is just a stress inducing diagnosis for everyone.