I have been on the big 3 for 3 months now. Because I have a doctor who is into preventive medicine - apart from my lung doctor, she stopped my cough last August within three days with supplements only she can get as a doctor. Find a doctor who is into preventive medicine - my blood tests show no damage to my organs. My lung specialist does not particularly approve or disapprove, and probably mentally pats me on the head. However my doctor on the Gold Coast is right on the ball. I coughed violently for 8 months, stopped within three days of seeing her, and have barely coughed since. I am tolerating the big three surprisingly well, and on the other days taking Dr. Elen's supplements. She gets them from New Zealand. By the way I am on the Gold Coast in Queensland Australia.