← Return to (MAC/MAI) Mycobacterium Avium Complex Pulmonary Disease: Join us
Discussion(MAC/MAI) Mycobacterium Avium Complex Pulmonary Disease: Join us
MAC & Bronchiectasis | Last Active: Oct 29 5:15pm | Replies (9350)Comment receiving replies
Replies to "@windwalker @heathert @spencersok @jkiemen This is the email I received from the CEO of Vast Therapeutics..."
@pfists @jkiemen @heathert @windwalker Thanks for following up on this Shari. We could have guessed as much from their website -- they seem to want to focus mostly on active cystic fibrosis.
Fairly similar numbers of people are diagnosed with NTMs each year compared to the numbers diagnosed with active cystic fibrosis. But those with active cystic fibrosis are diagnosed far younger, often as children. (NTMs are regarded as ONLY an 'old people's disease', although that isn't true -- 50% are younger than 65 and some are children).
There's been research around for 15 years that NO can reduce pseudomonas aeruginosa, but Vast has a new and better delivery system to try out.
The Vast Therapeutics study we looked at showed success with NTMs (https://cysticfibrosisnewstoday.com/2018/05/24/vast-therapeutics-bioc51-fares-well-mouse-studies/ or https://www.prnewswire.com/news-releases/vast-therapeutics-formerly-novoclem-announces-results-showing-eradication-of-all-in-vitro-tested-multi-drug-resistant-bacteria-and-a-99-reduction-of-nontuberculous-mycobacteria-ntm-in-animal-model-300652648.html).
Past methods for inhalation of ordinary NO gas didn't work to get rid of NTMs or TB, but this new controlled release system Vast has developed does seem to be effective with NTMs.
It's a shame that people with NTMs haven't got the political clout to lobby drug companies to promptly pursue successful research results for NTMs. I wish there was something we could all do about that!!!
Anyway, there seems to be another study with NO for people with NTMs underway at University of South Carolina in 2018-2019, although it's not clear if they're using the new controlled release systems or not: 'A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection' -- https://clinicaltrials.gov/ct2/show/NCT03748992 . (Principal Investigator: Patrick Flume, Medical University of South Carolina). Does anyone know anything about this trial?
@pfists Fingers crossed all right, heres hoping, just wish it diddnt take so long.
For some of you who has no result in stopping their cough with traditional medicine may want to try herbal medicine like clear lungs. One effective therapy is CHINESE ACUPUNCTURE is very effective to help many lung problem. I found this effective CHINESE ACUPUNCTURIST in St Petersburgh Florida. Dr Su Liang Ku on the 2798 66th St. N. 727-541-2666 . This 77 years old man has 50 years in General/Family Practice Acupuncture, Tuina, Herbal Medicine etc. For those of you interested I guarantee you won’t regret it. He really knows what he is doing. His session cost 70$. Just wanted to share this possibility with you. Have a great week! We are going back to Canada Tuesday morning! Nic
To pfists. Thank you