I could not tolerate any of the AI drugs. My weight ballooned while I tried to stay on them. It took a year to get it off. I was 266 pounds in the end. It is a year later, I have completely changed my way of eating, and I am now, since June 15th, under the 200 mark. I walk again, and exercise, and live my life to the fullest..... A healthy diet was my answer. 2 years cancer free. I have a goal of 100 pounds by next June 15th.