Below each Podcast (like this one https://connect.mayoclinic.org/blog/podcasts/newsfeed-post/boosters-reduce-vulnerability-to-covid-19-variants/) is a place to press "Comment." Type your message, then press "Reply."
The responses are monitored. I'm not sure that you will get a personal response, but questions asked there usually find the way into a subsequent Podcast. As with all of Mayo Connect, you are unlikely to get specific medical advice, so if that is your desire, please contact your own providers.

Does this help?
Sue