I've was diagnosed with PN five years ago at age 58. Symptoms were mild at first but now feet are numb and am taking Gabapentin. PN is beginning to happen in both hands. I asked to increase the Gabapentin dose but my neurologist instead recommended Alpha Lipoic Acid because he thought it would help without introducing serious side-effects. I used ALA for a few weeks but began to have serious reflux issues and discontinued. So, was initially interested in Protocol 525 discussed in this thread, but the first ingredient in the 525 list is Na-RALA which is a form of Alpha Lipoic Acid so now not so sure, but perhaps will try it for a few weeks and see. My wife suggested taking Omeprazole for the reflux.