Do not let yourself suffer from the meds. I could not take Rifabutin at all, but do beautifully with Rifampin which is the sister. Squawk if one of them is making you sick. They can change it out and they should or get a new doctor. My doctor in Tyler would never have let me suffer or be in bed from the drugs. I read where these poor patients spent a year on the couch. Ridiculous and not necessary.