@yaggie01 Hi there, and welcome to our group. I was happy to see that you have read many of our posts and are gathering your information. It is the smartest thing you can do. You will find that YOU will be your own best advocate. Are you able to navigate our site alright? Do you know about using the Discussion Board to find topics? Or entering key words in the 'search' box at the very top of this thread? I am here to help. I am glad that you are going on the Arikayce. Meds delivered straight to lungs are supposed to be better for your body. I didn't really get well after 10 yrs of being extremely sick; until I was put on inhaled tobramycin. That was my magic bullet. (Btw, I never got on the Big 3). Will you please stay connected with us and report back how you do on the Arikayce? Thnx!