Hi John. I appreciate the great reference material. I’ll spend some time on each.

I have been a reluctant researcher on MECFS since ~1990, and joined several of the forums in that arena. My home office is stacked high with research journals and articles from several sources you referenced=/ Cort Johnson has done a terrific job in setting up phoenixrising.me forums and Health Rising.org/forums, the 2 largest and most actively involved.

When you say you’re studying the metabolic connection I’m wondering if you’re referring specifically to the digestive system involvement? If so, I am also interested in learning more about it and IBS. My ‘gut’ feeling (pun intended) is that there is some strong correlation. My gut problems recently began and it feels like it’s being affected by nerves
(related to the SFN)? I recently scanned a book ‘The Second Brain’ that espoused the stomach as having its own nervous system, in addition to producing over 90% of the body’s serotonin. Dr. Mike Gershon went on to claim that it, the stomach can therefore function independently of the brain! Pretty interesting stuff, seeding more interest… .

I look forward to learning of your related ideas and those of others. Many thanks.