Hello Microbe1943 -- Your brief history is amazing! I can't imagine how resilient you must be to make it through all you've been diagnosed with and suffered through. Since PMR followed within 2 days of my senior flu shot, I now have the same unwillingness to take the "booster" shot for Covid for fear of setting my "overactive" immune system into even higher gear -- I already had 4 other immune-related conditions. The idea that ALL 65 and older individuals need the adjuvanted quadrivalent flu vaccine seems like WAY too broad a category. There is no proof that a 'pumped up' flu shot DOES trigger a body storm in immune-compromised individuals, and there never WILL be proof unless follow-up studies are done that specifically target that population. Nevertheless, however 'wonderful' the booster may be on its own, my system had a melt-down following the flu vaccine and I just can't take the chance of creating further havoc. Only a month went by before I was diagnosed with PMR, but during that time as the disabling pain spread and grew in ferocity I had reached the stage of 'not wanting to live like this any longer'. Thankfully, prednisone (with all it's side effects) does mostly manage the pain and I've been able to resume many of my old activities - but I dare not risk pushing my body farther than it is able to go. You have weathered SO MUCH and I admire your mental toughness and general attitude! Thank you for sharing your story.