@dglaude First, welcome to this supportive, informative group. I've learned much here, and recommend you do the same. Do a keyword search for posts about alternative treatments to the "big 3" as many knowledgeable docs are now avoiding that old school treatment protocol...some of us have been on just one antibiotic, others have rotated, others have been on inhaled Amikicin (sp)... first, make sure your doc cultured your MAC specimen taken during your bronchoscopy to determine the right antibiotic to use on your particular strain.