Firstly, very sorry to read about your losses. I have been on buproprian on and off for 20 years. I too, get depressed when experiencing loss. I used to resort to alcohol but that doesn't work!! Buproprion works very well for me. I even experienced a small weight loss taking it while I dealt with my sorrow and grief, never to put weight back on after I quit taking it. It is cheap also. I had no side effects. I have had a life filled with sorrow and loss, too. My entire family is gone and 6 months ago my house burned down and I lost my 'fur buddy.' 100% loss. All I had was the clothes on my back. I am starting over and started on the bupropion again. It takes a while to work, but it is worth the wait.