@brigby To answer your questions, I didn't start with IV antibiotics. By the time my condition worsened (spring 2017, after living with bronchiectasis diagnosis since 1997 and NTM diagnosis since 2008) I was retired from full-time work. I still work part-time and I've been working around the Monday, Wednesday, Friday doses of the 3 antibiotics. On those days I like to stay home in the afternoons to be close to my own bathroom and be able to rest if I need to rest. But I have to say those days are getting easier as time goes on.