@hydrang3a I was on Amakacin liposomal (inhaled) which is the same as Arikayce, for a year., I had no trouble getting used to the whole process, it was a bit time consuming but worth it to me. I never had the IV Amikacin but I have heard that liposomal is alot easier on the body Thats great that you start on Monday, at first you may lose your voice so make sure you have strepfen lozengers, they are anti-inflam/ antibacterial which goes straight to your throat (it was fantastic for my voice) and rinse your mouth out each time you finish Arikayce, Hope it all goes well for you and dont hesitate to ask anything.