I am being enrolled on a clinical trial for Trikafta in the next month at Emory U in Atlanta. I have the one required mutation and medium sweat chloride along with bronchiectasisand history of MAC and other lung infections. My regular pulmonologist referred me to the CF pulmonologist who prescribed it for me after I explained that my niece has benefitted greatly due she has two CF genes instead of 1, and was born with CF. My insurance denied it twice. Will see whether the 30 days on Trikfafta helps. If not there is new drug coming out next year not approved yet by the FDA bransatocib? cannot remember the exact spelling.