@athenalee , Thanks, my friend. As I learn more and more about genes, I become, like you, more aware of stuff I reLLY DID NOT SEE EARLIER. Whoops, the cat just decided to help me. Anyway, Sjogren's is one that really makes a mess out of many diseases which would be almost irrelevant otherwise. LGMD2m, AGel (GSN), Cardiomyopathy, CPVT. Lissencephaly, Clarkson's, etc. Chronic Leukemia. And infections and many environmental issues just add to the pile. All this can take a simple issue like cancer and make it just awful. I apparently am getting ready to undergo another basal cell removal from my face. 54th cancer surgery. And for some better understanding of what we go through with Sjogren's and this other stuff, watch "Apollo 13" again, and pay attention to the emotions, especially of the men and their families as they struggle with their lives and events. Take care. @oldkarl