I found myself acting very emotionally erratic after about 2 weeks of taking just half the prescribed dose of Raloxifine. I'm usually a happy person. I realized that this was how i felt when i started mesopause and found myself sobbing because my daughter hadn't cleaned her room. I knew that was nuts. I was put on estrogen then and i was fine as I could be through my husbands' Parkinsons, dementia, death and then my cancer. I need some estrogen. Life isn't good without it. I'm stopping the Raloxifine today and will talk to my oncologist about it next week when i go for chemo.