Hello @churchaustin2 and welcome! @jenniferhunter has come in and shared one approach to explore and rule out before doing more in-depth diagnostic testing, etc. Also, @jwillits8 suggested exploring a test for Lymes Disease.

The truth is, what your wife is experiencing could be so many different things and for that reason, it may be best to consider the trip to Mayo Clinic in Rochester, MN as you mentioned. At Mayo, departments work together across departments to diagnose and treat, making it a key differentiator over other hospitals, and allowing patients answers quicker because of the coordinated care. If you decide to explore making an appointment, it is as simple as starting with this link: http://mayocl.in/1mtmR63

What is the soonest you can be seen in Canada?