Hello All,

I have Mac diagnosed 2.5 years ago went on big 3 for 2 years. Recent follow up ct showed new nodules culture positive for Mac awaiting antibiotic susceptibilities now. Treated locally by pulmonologist who is sending me to new local ID specialist. May also get second opinion from National Jewish as well which my local doc is happy to send me to if I want. I hoping I don't have any antibiotic resistant strains and can start on big 3 again as well as Arikayce the inhaled amikacin. Question... for those that are on Arikayce did you your Dr. put you on IV antibiotics first or start you directly on the inhaled version? It seems that the inhaled form has better lung penetration and less likely to cause systemic side effects like renal failure and hearing issues so would prefer to go that route. I don't have bronchiectasis just long term asthma treated with Flovent that I think made me susceptible to Mac. I'm off the Flovent now but was just on a reduced dose my first round of the big three. Thanks