Hi John, Based on what i've picked up from you and a few other credible sources of info, i think i will try the Protocol 525, despite the fact that i'm hesitant because of ALA ingredient and my hypo thyroid/levothyroxin issue which i have read is a reason to be careful. I have consulted my endocrinologist and we will do a blood test in about 3 months from the start of the program. Since my sensory nerve neuropathy has become quite aggressive of late, spreading to my upper limbs and back and chest for no apparent reason, I have to try something, whatever the cost. Thanks for your input on this product.