I loved the downtown close to the clinic but alas the rates are higher and we were there for months at a time. The shuttle ran every hour from all of the different Mayo buildings to the different hotels during the day. They tell you which color your shuttle is and we had the same driver every day. We found better hotel rates outside of downtown, and very much enjoyed the shops and dining downtown during the day and the more relaxed setting in the evenings. We stayed at Townplace suites so there was a host of places for dinner within walking distance. I would however not recommend the international guest house. I hate to say it but it was so bad, I scrubbed everything with bleach and then still couldn’t be comfortable so I ate the fee and checked out, luckily it was winter and a few less people so we got our one bedroom at townplace.

Hi @amywood20, I can't speak for the Hyatt shuttle, but I do know that downtown public transportation is very reliable because of the weather. However, the subways are definitely a perk to staying in one of the hotels closer to campus.