@tsc and @hmccarth5. Yes, the evil Prednisone! I have had Giant Cell Arteritis since 2019 and lost most of the vision in my right eye before being hospitalized and given 1000 units of Prednisone by I.V. over a three day period. Had a stroke on the 2nd day (July) and another stroke in September, but Prednisone saved the eyesight in my left eye. Both strokes were classed as small, so did some,but minimal, damage. I was on Prednisone for a year before my new rheumatologist put me on weekly injections of Actemra, a medication specifically designed for GCA. Much easier on the system! I was on both Prednisone and Actemra for several months when my weekly lab results showed that my WBC and neutrophils had bottomed out, and I was immediately taken off both until my lab work crept back to normal. I resumed weekly Actemra injections (no more Prednisone) and over time, all the nasty results of Prednisone disappeared, including the awful weight gain, hair loss, itching, moon face, etc. So happy to be back to my old self! I'm now only on Actemra injections every two weeks and my rheumatologist is VERY pleased with my progress. She didn't even recognize me because she met me at the height of my Prednisone period. So have hope, folks, all those nasty changes in your body will disappear once you're no longer a victim of that lifesaving, eyesight saving Prednisone. It's such a wonderful medication when we are in dire need of it, and we have to be thankful we have it for those critical times in our lives. Laurie ❤