My daughters iron never went back up either with iron supplements. The only thing it went up with is a blood transfusion. She will start iron infusions next week. I am hoping it goes up further. The lowest her hemoglobin got was 5.8 which is not good. Her folate levels were the lowest the hematologist has ever seen. She has O- blood type. I'd be interested to know if there is anything that is common in those on this commentary.