No reason to hit the panic button. You may want to consider having several more USPSA tests 90 days apart to determine if the change is a continuous upward trend or fluctuations. If those tests continue to rise then you may have other decisions to consider with your medical team. You will want to gather clinical data...

The first may be whether to image, when, at what PSA and with what? The PSMA scans recently approved by the FDA can detect at <.5 but as your PSA goes up, so does their detection rate.

If your PSA continues to rise then you can calculate PSDAT and PSAV.

You may want to discus Genomic testing with your medical team.

Informed by clinical data, you and your medical team can make a decision about treatment, whether to and if, when to initiate, with what, for how long, how to monitor response...

In my case, I was diagnosed in Jan 14, had RP in March 14, BCR in Dec 15, SRT in Mar 16 then in Jan 17 did 18 months of ADT, six cycles of taxotere and 25 IMPRT to the PLNs, finished treatment in May 18.

My PSA has fluctuated over the last three years. My medical team and I continue to monitor every 2-4 months and have decision points:

Need three or more tests 90 days apart with continuous rise and calculate PSADT and PSAV.

Image between .5-1.0

Then decide on treatment.

Here's my recent PSA tests:

2018

12 February 2018 Testosterone <7, PSA <.1 (Mayo)
27 April 2018 Testosterone <3, PSA <.1 (SMC)
1 August 2018 Testosterone <3 PSA <.1 (SMC)
30 October 2018 Testosterone 135 PSA <.1 (SMC)

2019

2 February 2019 Testosterone 481, UPSA .36 AHC
16 February 2019 USPSA (AHC) .3
2 April 2019 USPSA KCUC .06
7 June 2019 (USPSA KCUC).124
19 August (USPSA KCUC) .06

2020

3 January 2020 USPSA (KCUC) .07
5 May 2020 USPSA (KCUC) .07
4 August 2020 USPSA (KCUC) .09
5 November 2020 USPSA (KCUC) .16

2021

5 February 20221 USPSA (KCUC) .29
30 April 2021 USPSA (KCUC) .3
12 July 2021 USPA (KCUC) .17

Kevin