← Return to Prepping for CAR T Therapy: What is the process like?

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Hello @blewellyn - Welcome to Mayo Clinic Connect a place where folks can share their experiences which will hopefully help others.

I had Large B Cell Lymphoma so my treatments prior to Car T would be different than your moms. Prepping for Cart was not particularly difficult, having all the pre therapy tests was quite typical, the apheresis process (Took about 3 hours) to harvest the cells was very straight forward. I underwent 3 sessions of chemotherapy prior to the modified T Cell infusion. Once the cells were modified, the infusion of the new T - cells was very simple. It was the second day after that that I started to encounter side effects. I had pretty much all the published side effects that we were told about. Neuro toxicity, Cytokine Release Syndrome (CRS), slow heart rate, high fever. I spent 2 weeks in hospital one of them in the ICU. I encourage you to take note of all the side effects that are described to your mom by her practitioner. I was extremely weak for some time after I left the hospital.

I hope you find this information helpful, be cognizant of the fact that side effects and their degree can be different for everyone. I am so glad that you will be along to support your mom, I remember I was instructed to have a caregiver at my side for six weeks post infusion, this was excellent advice as I would not have been able to manage on my own as an outpatient.

When is your Mom scheduled to have her treatment start?


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Replies to "Hello @blewellyn - Welcome to Mayo Clinic Connect a place where folks can share their experiences..."

Hi Bob!
Thank you for telling me about your experience. Right now we are prepping with venetoclax and ibrutinib, she started that last week. She will have weekly admissions to ramp up the dose of the venetoclax until maximum dose is achieved.

Dr. Wang said he hopes her T Cells are ready to be harvested around December. Luckily I am able to take FMLA and be with her through the whole process, including post CAR T infusion. I'm a nurse, but my specialty is Respiratory, so some of this is a new ball game for me.

I really appreciate hearing about your experience, Bob! Do you mind if I ask how long you have been in remission?