I have posted before about this, my side effects from Anastrozole were not severe until I had been on it about 18 months. The joint pain and stiffness was so bad I couldn't walk, I now have osteoporosis, and had so much trouble sleeping that I was only getting three or four hours of sleep a night. I stopped taking it in March and it has taken this long to feel better, I still have days where I am very fatigued but am sleeping so much better. This decision is not for everyone, it will be two years since my surgery in December, I go in every three months for an exam and blood work, for me quality of life and being able to move were the deciding factor. I have no interest in Tamoxifen and feel switching to a different type of drug won't help. It's a journey, I am 76 years old.