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Do aromatase inhibitors (like anastrozole) cause weight gain?

Breast Cancer | Last Active: Sep 8, 2021 | Replies (61)
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@pammyt

I have been taking Letrozole for 9 months now. I have chosen it as my only treatment for stage 4 bc in my bones. It shrunk the tumors and now I am in remission without new growth or mets, but I have noticed in the past month a change in bowel habits. I am constipated and bloated followed by diarrhea. I was camping and riding in the side by side this past weekend with my husband when I started having stomach cramps and had to find a bathroom quick! I have been home the past couple of days and today is the same. The only constant is the Letrozole.

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Chris, Volunteer Mentor | @auntieoakley | Sep 8, 2021

I can tell you this is not uncommon for a lot of drugs. The way it was explained to me was keeping everything regular prevents the see-saw effect of constipation and then diarrhea, for me it is Mira lax, every night. For my husband it is dulcolax every afternoon. Please talk to your doctor, no one should have to live this way. I went through what I refer to as death cramps. Have you talked to your doctor about this?

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