Can Severe (electric shock-like) Pain be a sign of Regeneration?

Posted by ranchan @ranchan, Aug 29, 2021

Hello, I'm writing here on my sister’s behalf in an attempt to find some reasonably solid answers to the question posed in the title of this discussion.

I have been able to find tantalizing clues online that suggest that peripheral nerve regeneration can be accompanied by tingling and pain, but nothing that seems particular to my sister's circumstances. What follows is an attempt to frame the question more specifically, and to ask if such a supposition even makes sense in my sister's case.

In a nutshell, and based on a variety of symptoms and an MRI, she was diagnosed with Cervical Myelopathy - I'm not sure about any further specifics, i.e. which numbered vertebrae are involved. She has had two surgeries. The 1st was by a spine surgeon who implanted a bone graft, and the second was by a neurosurgeon who removed the bone graft (while condemning that approach in no uncertain terms) and proceeded to fuse certain vertebrae - again, I'm not sure which ones. Subsequent to the second surgery she was in a neck brace for several months and unable to take any steroids or OTC pain relief meds as they can inhibit bone growth. Once she was able to remove the neck brace, and based on an evaluation of her progress, she was told that this abstention from steroids, et. was to continue for at least another 6 months.

Around the middle of month three and after considerable improvement of many the more painful symptoms, she suddenly started experiencing what she described as unbelievably painful electric shocks in the ulnar region of her left hand - pain that, at it's worst she said was comparable to child birth contractions. In response she was given prednisone. Five days after an initial round the pain returned and she was given a second round. She just had an emg done which did not show anything that would account for the severe pain. She has other appointments scheduled for this week, but thus far no one has advanced a workable theory to account for these pains, or put them into perspective - much less how to mitigate them going forward.

Numbness (etc., in her left hand), and loss of function in the pinkie & middle fingers, and to a similar, but slightly lesser extent on her ring finger were some of the initial symptoms prior to diagnosis, and have progressed significantly since then. But the excruciating pain in the left hand is completely new & unprecedented.

So, given the above, and based on the collective experience of this group, I’m asking if the supposition embedded in the title question (“Can Severe (electric shock-like) Pain be a sign of Regeneration?”) could actually be a positive consequence of the second surgery, or largely an exercise in wishful thinking?

I would greatly appreciate any wisdom (anecdotal or otherwise) on the subject that anyone would care to offer!

And finally … My sincere thanks (and apologies) to anyone who has had the patience to read this all the way to the end!!

Interested in more discussions like this? Go to the Neuropathy Support Group.

@johnbishop

@jgraber here is the Chronic Pain group page that shows all of the discussions in the group mentioned by @efgh1020

Chronic Pain Group - https://connect.mayoclinic.org/group/pain/

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Thank you, John. I also have a positive smooth muscle ab titer and ANA and that is possibly indicative of autoimmune hepatitis. My Dr. said you can have muscle, bone, joint pain and small fiber neuropathy with this. I was hoping to talk to someone who has this diagnosis and similar pain? I went on the autoimmune hepatitis group but they were mainly talking about younger people who have this diagnosis. I know this condition is more common in women. Thank you!

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@jgraber

This is the first time in 20 years I’ve talked to other people dealing with this horrific nerve pain. This means the world to me. Thank you. I love your analogy of “comet” pain. I completely get that. I have severe nerve pain that happens throughout my body now but it seems like the area speaking loudest is what I feel. Doctors ask what area is the worse and that is hard to answer because it changes. Sometimes I feel like a knife is stabbing into the rectum, shooting pains from the hip region down my legs, severe bearing down pain over sacrum like back labor, deep aching, horrible leg pain, feet pain, hands on fire and pain up my arms, strong vibration sensations in both hands simultaneously, Feeling that I’m wearing tight gloves and socks when I’m not, neck pain shooting over my head, painful scalp area on the right side of head with shooting pain and very tender to touch, migraines, upper right abdominal pain, intolerance to cold and hot temperature (cold air feels very painful and I overheat easily and I’m way past menopause), etc.

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I'm now blessed with this peripheral neuropathy from having breast cancer. Started a month ago. Oncologist said it would go away; didn't offer any medication for it. Bottoms of both feet at first sign of it. Now both hands slightly numb. My left foot is worse with it up to my ankle area also. I have lightheadedness most of the time when standing. I started ny research just recently here. In reference to Chemotherapy induced peripheral neuropathy (CIPN) The two drugs being used for treatment are; duloxetine and pregabalin. It also affects my quality of life. Also found other treatments being tried in trials, such as low frequency electro stimulation device and acupressure clinical trial protocol and ear randomized controlled trial; whatever those last three means just don't sound up my alley. I also have something else I'm dealing with right now, which I did post in the gastroenterology post. Achalasia type 111 and epigastric (small hiatal hernia), which I'm seeing my general surgeon about a possible procedure for it tomorrow. I thought maybe my lightheadedness was due to it, but from what I have read about this chem related neuropathy; it's most likely causing my lightheadedness which is getting worse. Any words of wisdom for me is greatly appreciated. Especially as far as any medication advice. I would like to have some knowledge of any medication to ask the doctor tomorrow. Thank you, Doris

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@d13

I'm now blessed with this peripheral neuropathy from having breast cancer. Started a month ago. Oncologist said it would go away; didn't offer any medication for it. Bottoms of both feet at first sign of it. Now both hands slightly numb. My left foot is worse with it up to my ankle area also. I have lightheadedness most of the time when standing. I started ny research just recently here. In reference to Chemotherapy induced peripheral neuropathy (CIPN) The two drugs being used for treatment are; duloxetine and pregabalin. It also affects my quality of life. Also found other treatments being tried in trials, such as low frequency electro stimulation device and acupressure clinical trial protocol and ear randomized controlled trial; whatever those last three means just don't sound up my alley. I also have something else I'm dealing with right now, which I did post in the gastroenterology post. Achalasia type 111 and epigastric (small hiatal hernia), which I'm seeing my general surgeon about a possible procedure for it tomorrow. I thought maybe my lightheadedness was due to it, but from what I have read about this chem related neuropathy; it's most likely causing my lightheadedness which is getting worse. Any words of wisdom for me is greatly appreciated. Especially as far as any medication advice. I would like to have some knowledge of any medication to ask the doctor tomorrow. Thank you, Doris

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@d13 Both pregabalin and duloxetine have dizziness as one of the side effects. You might want to discuss it with your doctor.

-- Pregabalin: https://www.drugs.com/mtm/pregabalin.html
-- Duloxetine: https://www.drugs.com/sfx/duloxetine-side-effects.html

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@johnbishop

@d13 Both pregabalin and duloxetine have dizziness as one of the side effects. You might want to discuss it with your doctor.

-- Pregabalin: https://www.drugs.com/mtm/pregabalin.html
-- Duloxetine: https://www.drugs.com/sfx/duloxetine-side-effects.html

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Thank you, I won't even bother with those two, because that is the one major symptom I'm trying to get rid of. This is terrible if there isn't anything without any side effects to take to get rid of my lightheadedness everyday. So far I'm coping with the numbness in my feet hands, but now after all that I have read, it will be getting worse. Even though the oncologist said it will go away. Not happy now with his answer. I guess my time was up with him that day! Lol

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