Well, u hope you find a solution. PMR sucks. Everyone that has it is different from everyone else, meaning that we all have a different chemical system, therefore, we all react differently than everyone else. We would be discussing this for years trying to figure out what those differences are. Are you a smoker? Canibis? Drinker? Allergies? Supplements? ETC. What's working for me doesn't always work for anyone else. I hope you find your way with this. 😊