Hi Kerry I just wanted to check in and let you know you won't be hearing anything from me for a couple of weeks. I will be off the Internet for awhile. Unfortunately, I did not have results from using the Prunelax after one week. I know there may still be some adjusting I need to do. But, one night I took 4 in the evening and I did have results. I also had some very uncomfortable cramping but that happens with Bisacodyl also. It was pretty intense. I tried taking 2 tablets in the morning and 2 at night for a week and it didn't do anything, so to speak. So now I'm "playing" with the dosage. I also bought some Senokot and can't really give a report on that. I'm thinking my system needs more than the usual dosage because of my "tortuous intestine"/long, slow transit time. Thank you for all your support and I won't give up. Say "hi" to your son for me. I think of you both often. Take care of yourselves and I will check back in September. Jacque