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Does Prednisone weakened your immune system while being used for PMR

Polymyalgia Rheumatica (PMR) | Last Active: Feb 5, 2023 | Replies (21)
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@loribmt

Hi Alan, yes prednisone does suppress the immune system, even at a low dose. It takes a while after a slow taper to stop prednisone without any side effects of withdrawal. Once you’re completely off, it can take several weeks for your adrenal glands to start producing cortisol on their own again. That’s difficult to predict exactly how long that will take.

I found a couple links you might find interesting regarding steroids and how they affect the body.

Are you beginning a taper to get off prednisone?
https://www.mayoclinic.org/steroids/art-20045692
https://www.mayoclinic.org/prednisone-withdrawal/expert-answers/faq-20057923

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Replies to "Hi Alan, yes prednisone does suppress the immune system, even at a low dose. It takes..."
alan bruce | @alanbruce | Aug 14, 2021

Thank you for your response. I finished my low dose taper 2 years ago following the Mayo protocol. I do get injections in my shoulders twice a year and I am not sure how these impact the immune system.

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