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Anti biofilm attributes of Curcumin

MAC & Bronchiectasis | Last Active: Dec 30, 2021 | Replies (18)

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@sueinmn

As with any supplement, be careful with curcumin - it has some interactions with other drugs and supplements. Read about them, and possible side effects here.
It is best to consult with your provider before starting any new supplements

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Replies to "As with any supplement, be careful with curcumin - it has some interactions with other drugs..."

Hi Sue @sueinmn and Lynne @lynne63, you're right, there is growing research evidence about the effectiveness of Curcumin in its most bio-available form for treating infections and disrupting or inhibiting biofilm. The best most-bio-available formulation I've found is called 'Doctor's Best' -- which you can buy online, but it is expensive!

And Sue you are also right about the risk of interactions between Curcumin and some drugs. Before we buy it and take it, we need to get advice from pharmacists or look up the drug interactions ourselves.

If you are taking TB meds like Azithromycin (or Clarithromycin), or Clofazimine, please note that research on Curcumin shows it is a potent hERG blocker. In other words, the interaction of these TB drugs with Curcumin can cause long QT in the heart, or increase it. Long QT is a serious heart rhythm problem.

(Because you've had long QT, Heather @heathert please DON'T use a highly bio-available form of Curcumin, or don't use it at all while you're on Azithromycin. Plain Turmeric powder is okay, no problem).

I need to take both Azithromycin and Clofazimine, and have already recorded long QT a few times from the interaction of those 2 drugs . When I used the highly bio-available Curcumin as well, I got even worse long QT. The doctors told me to stop using it.

BUT I definitely do plan to use highly bio-available Curcumin again, after I'm able to stop taking the Azithromycin and Clofazimine TB meds.

So yes, Curcumin does look like it could be a very promising treatment for us, but we need to be careful of interactions with our TB meds first.