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Anti biofilm attributes of Curcumin

MAC & Bronchiectasis | Last Active: Dec 30, 2021 | Replies (18)

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@kathyhg

I’m also curious about whether the curcumin was taken in pill form or nebulized/inhaled.
Thanks

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Replies to "I’m also curious about whether the curcumin was taken in pill form or nebulized/inhaled. Thanks"

Here is the article I found describing the research project: https://www.researchgate.net/publication/321382576_Curcumin_an_antibiotic_resistance_breaker_against_a_multiresistant_clinical_isolate_of_Mycobacterium_abscessus

This is a summary of the findings, based on tests of the combination of antibiotics & drugs on Mycobacteria Abscessus on slides: "Overall, the present findings lend support to the notion thatcurcumin is a potential antibiotic resistance breaker, that is, a com-pound capable of restoring the effectiveness of failing antibiotics byreducing their MICs (Brown, 2015). The strong effect of curcuminand amikacin on biofilm reported herein emphasizes the significanceof their synergistic association. Further work on the ability of curcuminto synergize with antibiotics against M. abscessus infections is warranted"

I cannot find any current articles on actual in-body testing. There is a study of the effect on dental bacteria from 2020, but again it was conducted on slides, not on people. (https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-020-01975-5#Sec10)

Does anyone else have a current article to cite, because this would be a real game changer for all biofilm-enclosed bacteria!
Sue