Thank you, @interest. I appreciate your comment..this sounds very similar to the onset of my symptoms. I, too, keep active--walk, bike, or ski, etc. I find that things are at least not worse if I do this, and my attitude is better for the most part. There are some very bad days, though, when I get discouraged and feel hopeless. I fear that my beloved wife also feels the weight of the burden. We both had lots of dreams for retirement--and, well, this was not one of them!