Hello @eyeman, Welcome to Connect. You will notice that we added a few words to the title of your discussion to hopefully better describe the discussion for members who may have experience or information to share with you.

I really had not heard of Berberine until you started this discussion. I did a quick search and it does sound promising and has been a part of Chinese and Ayurvedic medicine for thousands of years from what I've read. I would still talk with my doctor or a pharmacist before starting it as a daily supplement in case there are any concerns of interactions with any other supplements or medication that I'm taking. Here are some of the articles I found that you may have already seen but still may be helpful for other members joining the discussion.

-- Everything you need to know about berberine: https://www.medicalnewstoday.com/articles/325798
-- Efficacy of Berberine in Patients with Type 2 Diabetes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410097/
-- A New Therapeutic Candidate for Cardiovascular Diseases: Berberine: https://www.frontiersin.org/articles/10.3389/fphar.2021.631100/full

You may also be interested in the following discussion which mentions berberine in the description of the discussion.
-- What supplements are good for you as a diabetic?: https://connect.mayoclinic.org/discussion/what-supplements-are-good-for-your-as-a-diabetic/

@lewismustard, @deanna2, and @dorisena may have some thoughts to share with you on berberine as a daily supplement.

Have you talked with your doctor or pharmacist about adding it to your daily regimen of supplments?