John, Yes I did have the moderna shot months ago and really had no reaction to it. I can't remember now if I was having pain at that time. I was taking leflunomide along with the Pred for months and my pain level was good. I had severe reactions to the drug though, so they put me on oral Methtroxate instead. That was about 4-5 months ago. I can't tell if it is working because as I taper from 5mg to 4mg my pain is getting worse each day. I am supposed to taper to 3 in a week and I don't see that happening. That is why I am questioning infusions. My doctors have told me in the past that they believe I may end up on them, I'm a very healthy, positive person and I ignored that, thinking I would heal quickly with a good attitude and taking the drugs as directed. Well, I guess I am finding the reality of what this condition really is and that it is not easy to get into remission. So, now I will have a serious discussion with my rheumatologist about the infusions. I haven gotten a response from anyone who has tried them on any of these support groups. It sure is nice though to connect with others who are suffering with the same condition rather than just doctors who have not. Thanks for being there!