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Are you taking Reclast for osteoporosis?

Osteoporosis & Bone Health | Last Active: Feb 14 5:27am | Replies (267)

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@rashida

@lioness it seems there’s no difference between Prolia and Reclast, except Reclast is taken once a year and Prolia is taken twice a year. Are they both from the same company?

https://www.drugs.com/tips/reclast-patient-tips

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Replies to "@lioness it seems there’s no difference between Prolia and Reclast, except Reclast is taken once a..."

Reclast is zolodronic acid, a bisphosphonate. Prolia is a monoclonal antibody. (Fosamax is a bisphosphonate.) If I read it correctly, the bisphosphonates were among the first drugs approved to treat osteoporosis but seem to falling out of favor. In part because of the rare side effect of osteonecrosis of the jaw, aka BRONJ aka bisphosphonate-related-osteonecrosis-of-the-jaw. (A few cases of which Prolia has since been associated with too now.)