@lp8 I’ve had the vest for awhile now also, I think by sitting upright though gravity plays a role in the movement of the mucus. I also believe the biggest factor is the location (lobes) of where each individual’s worst Bronchiectasis is. Mine is posterior both lower lobes, and middle right. Being lower lobes means it has to travel farther of course to the larger central airways to help expel. I’m still trying everything possible, now doing vest with postural drainage, after 7% nebbing followed by 2-3 sessions of Autogenic drainage. My whole morning session takes about an hour, but for me well worth it in order to feel better throughout the day.