Yes, I started my second chemo cycle on Friday. I got a port installed in my chest which makes it easlier to administer the chemo and draw blood. This second time around is effecting me a little harder. I am feeling a little more fatigue easier, Monday I slept for most of the day. A little more nausea than usual. Not too much of an appetite, but forcing myself to eat more small meals to keep my weight up. So far so good.