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@amandajro

Hello @bet. I can see you would like to connect with members who have experience with the MTHFR mutation. I'd like to introduce you to @gldnrtrvrlvr who has shared about also having MTHFR and may have feedback from consulting with her doctor.

There is so much to still learn about COVID-19 and other health conditions that all the answers are not available as we would all like, so in most cases, consulting with your personal doctor may prove to be the best until there is more widely available recommendations. Also, it seems as though everyone reacts very individually to the vaccine.

Are you wanting to get the vaccine?

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Replies to "Hello @bet. I can see you would like to connect with members who have experience with..."

I have MTHFR A1298C heterozygous mutation - which the sciense says does not put me at risk. Unfortunately I had a subclavian thrombosis at age 30 as a healthy, non-smoker, athlete, and was considered a high risk pregnancy during which I gave myself a shot of Lovenox in the belly every day for 9 months.
Fast forward to covid - I did fine with the first Moderna shot, not even a sore arm. The second booster landed me in the ER on day 3 due to disorientation and rapid heart beat. my D-Dimer was elevated but chest CT showed no evidence of embolism.

Before I could get the booster I got covid. Had two days of very mild symptoms - 100.2 fever and mild aches. Suddenly lost consciousness on day three which landed me in hospital for two days and had seizure like events for 8 weeks. Now five months after initial covid diagnosis I still have cognitive issues and am officially diagnosed with long covid.

I got the Pfizer booster last Friday and did fine until day 3 when started having mild "brain fog" and felt fluid in my lungs - constant need to clear throat. Chest CT showed 4mm pericardial effusion. Waiting to get EKG and Echocardiogram this week. Dr suspects I am having an inflammatory responses to the vaccine and was cautious and is looking for more research to see if I need to forgo future boosters. I do not regret getting the vaccine and feel my covid would have been significantly worse if I had not been vaxed.

Curious if MTHFR is a factor in both my reaction to covid and the vaccines, or if it is something else.