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MAC: Just how well do nebs work, anyway?
MAC & Bronchiectasis | Last Active: Feb 7 5:44pm | Replies (88)Comment receiving replies
Hmm, not something I had ever researched, so I took a look on line - look what I found:
Hypertonic saline (6 - 10%) was effective at inhibiting growth of pseudomonas in Cystic Fibrosis patients: https://pubmed.ncbi.nlm.nih.gov/24587256/
And 7% saline, in combination with inhaled gentamicin it was 3X more effective than normal saline (.9%): https://www.nature.com/articles/s41598-020-61413-4
So the short answer is yes, it helps - the final answer is not yet determined, but if I were looking at pseudomonas treatment today, I would probably show these to my doctor and try to find a way to incorporate in treatment. When I had pseudomonas, I had to go through multiple courses of oral levaquin (which scared me) an in haled Tobramycin (which stole my voice.) This looks like it might be an alternative to consider.
Are you fighting pseudomonas right now?
Sue
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Yes, I had a bad case right before COVID started and was put on 10 days of cipro which helped and did not appear in cultures again til last week. So ID md has put me back on same for 10 days. 4 days in, feeling better. The 3%saline nebs, done faithfully throughout This past year and a half didn’t touch it. June exacerbation was probably all about the pseudomonas, but too tired to think straight. Learning as I go.