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Benign fasciculation syndrome (BFS)

Brain & Nervous System | Last Active: 5 days ago | Replies (359)

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@marvel61018

Hi everyone. This thread has been incredibly helpful. I'm 41 and have had BFS for about 6 months in my shoulder, in which I also have osteoarthritis likely requiring a complete replacement (consult in August at Mayo!). As with previous commenters, treatments so far for me have been pretty hit or miss, mostly miss. These include differing amounts and combinations of gabapentin and carbamazepine, both of which make me completely exhausted, including days where it's difficult to work. While I wait for Mayo, I'm unable to see a local neurologist, meaning it's up to me and my PCP to determine next steps. On here I've seen a few other treatments, these include:

Pregbalin (anticonvulsant). Is this similar to gabapentin and carbamazepine?
Cymbalta (an antidepressant in the SNRI category) I've mostly ruled this out, due to previous side effects with SSRIs. Has anyone had success with this, though?
Nortryptiline - a tricyclic antidepressant. I've taken trazodone for other stuff - is this similar?
Ropinirole - a parkinson's drug - no idea about this one. Experiences? Does this one knock you out, too?
Nupro - Not sure about this one - looks like a supplement? More info would be great.

Thanks all!

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Replies to "Hi everyone. This thread has been incredibly helpful. I'm 41 and have had BFS for about..."

Hello @marvel61018, Welcome to Connect. I have no experience with these drugs but can share a few references with you while we wait for other members with first hand knowledge to provide thoughts or experience with you.

-- (2005) Pregabalin: new drug. Very similar to gabapentin: https://pubmed.ncbi.nlm.nih.gov/16397976/
-- Cymbalta - Duloxetine (Oral Route) Side Effects: https://www.mayoclinic.org/drugs-supplements/duloxetine-oral-route/side-effects/drg-20067247
-- EFFICACY AND SAFETY OF TRAZODONE VS. NORTRIPTYLINE AMONG MIDDLE-AGED PATIENTS WITH MAJOR DEPRESSION: https://www.sid.ir/en/journal/ViewPaper.aspx?id=34173
-- Ropinirole: https://medlineplus.gov/druginfo/meds/a698013.html
-- GSK to discontinue RLS treatment ropinirole, maintain extended release tablets: https://aasm.org/gsk-discontinue-rls-treatment-ropinirole/
-- Neupro Patch, Transdermal 24 Hours: https://www.webmd.com/drugs/2/drug-148554/neupro-transdermal/details

Do you mind sharing what you were searching for when you found Connect?