@mims123 Good morning. Your brother sounds a lot like I did before I finally was diagnosed. I started vomiting for no reason and it got bad, but always in the morning. I could usually eat later but nothing tasted good. I needed assistance to walk and progressed to a walker. I was choking and coughing on water and my voice changed. I, too, lost 20 lbs. The doctors thought it ‘was all in my head’, and, in reality, it was. An MRI showed lesions on my brain. They didn’t know what it was and as they were debating, I got worse. I was finally admitted when I was non-responsive. My husband contacted the university medical center and the neurologist told them to do a brain biopsy and start high dose steroids.. As soon as we could, my husband too me to the medical center and they diagnosed an autoimmune disease on my brain. Suggest that your brother ask for an MRI. And see about going to a major medical center. They should be better at diagnosing strange things. I wish you luck and an answer for your brother. Will you let us know what happens and what you learn?